Current Methods of
Kidney Function Diagnosis Not Sufficient
Worldwide, incidences of terminal kidney failure are increasing rapidly. Identifying the onset of a chronic kidney disease at an early stage is a prerequisite for adequate therapeutic intervention. Methods known today for evaluating kidney function are, however, either precise but highly complex (clearance determination using exogenous markers) or easy to conduct but very inaccurate (clearance determination using endogenous markers or estimating kidney function based on blood parameters, such as plasma creatinine concentration). Due to this trade-off, the imprecise method is currently the one most often utilized. Consequently, this leads to an increase in morbidity and mortality, as well as to numerous avoidable kidney replacement therapies which entail substantial costs.
